Filming began in Thailand, Mexico, and the United States in January 2007, and ended in May 2007.

The rights were then sold to Nu Image and Millennium Films in 2005, who green-lit the film before the release of Rocky Balboa. Miramax intended to produce a fourth film but Stallone was unmotivated to reprise the role. The rights to the Rambo franchise were sold to Miramax Films in 1997 after Carolco Pictures went bankrupt. In the film, Rambo (reprised by Stallone) leads a group of mercenaries into Burma to rescue Christian missionaries, who have been kidnapped by a local infantry unit. The film is dedicated to the memory of Richard Crenna, who died in 2003 he had played Colonel Sam Trautman in the previous films. A sequel to Rambo III (1988), it is the fourth installment in the Rambo franchise and co-stars Julie Benz, Paul Schulze, Matthew Marsden, Graham McTavish, Rey Gallegos, Tim Kang, Jake La Botz, Maung Maung Khin, and Ken Howard. Rambo is a 2008 American action film directed and co-written by Sylvester Stallone, based on the character John Rambo created by author David Morrell for his novel First Blood.

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